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Claudia Richter

Cardiomyocyten im Chaos : Makroskopische Untersuchungen kardialer Arrhythmien in-vitro unter dem Einfluss elektrischer Pulsfolgen und Parameteränderungen

Universität Rostock, 2010

Abstract: For many physiological and pathological states in biological systems a complex spatio-temporal dynamic is characteristic. For example during fibrillation, synchronous contraction of the heart is disrupted by vortex-like rotating waves, resulting in complex and often chaotic excitation patterns. One focus of research is the clearing of underlying mechanisms of development and termination of such turbulence. Here an experimental setup was established, which allows investigation of cardiac pattern formation in two dimensional cell cultures under several conditions.

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