Stem cell manipulation and cardiac regeneration

Nan Ma

doi:10.18453/rosdok_id00001001

Nan Ma Dr.

Stem cell manipulation and cardiac regeneration

Universität Rostock, 2009

https://doi.org/10.18453/rosdok_id00001001

Abstract: Stem cell therapy holds great promise in the treatment of cardiac disease. A major limitation to the efficacy of cell therapy is the poor viability of the transplanted cells. Our present studies revealed that genetic modification of MSCs effectively protects transplanted MSCs against ischemia and increases cell survival after implantation. Continued development and application of genetic manipulation approaches in stem cells will undoubtedly lead to more efficient guidance and control of stem cell fate and improved stem cell function.

postdoctoral thesis free access

title:

Stem cell manipulation and cardiac regeneration

other title:

Stammzell-Manipulation und kardiale Regeneration [translated]

contributing persons:

Nan Ma , Dr.[VerfasserIn]
	136129765
Gustav Steinhoff , Prof. Dr. med.[AkademischeR BetreuerIn]
Axel Haverich , Prof. Dr. med.[AkademischeR BetreuerIn]

contributing corporate bodies:

Universität Rostock, Universitätsmedizin[Grad-verleihende Institution]
	1029510660

abstract:

Stem cell therapy holds great promise in the treatment of cardiac disease. A major limitation to the efficacy of cell therapy is the poor viability of the transplanted cells. Our present studies revealed that genetic modification of MSCs effectively protects transplanted MSCs against ischemia and increases cell survival after implantation. Continued development and application of genetic manipulation approaches in stem cells will undoubtedly lead to more efficient guidance and control of stem cell fate and improved stem cell function. [English]

document type:

postdoctoral thesis

institution:

University Medicine

language:

English

subject class (DDC):

610 Medical sciences Medicine

publication /
production:

Rostock: Universität Rostock

2009

identifiers: