Stem cell manipulation and cardiac regeneration

Nan Ma

doi:10.18453/rosdok_id00001001

Nan Ma Dr.

Stem cell manipulation and cardiac regeneration

Universität Rostock, 2009

https://doi.org/10.18453/rosdok_id00001001

Abstract: Stem cell therapy holds great promise in the treatment of cardiac disease. A major limitation to the efficacy of cell therapy is the poor viability of the transplanted cells. Our present studies revealed that genetic modification of MSCs effectively protects transplanted MSCs against ischemia and increases cell survival after implantation. Continued development and application of genetic manipulation approaches in stem cells will undoubtedly lead to more efficient guidance and control of stem cell fate and improved stem cell function.

Habilitationsschrift Freier Zugang

Titel:

Stem cell manipulation and cardiac regeneration

Weitere Titel:

Stammzell-Manipulation und kardiale Regeneration [übersetzt]

Beteiligte Personen:

Nan Ma , Dr.[VerfasserIn]
	136129765
Gustav Steinhoff , Prof. Dr. med.[AkademischeR BetreuerIn]
Axel Haverich , Prof. Dr. med.[AkademischeR BetreuerIn]

Beteiligte Körperschaften:

Universität Rostock, Universitätsmedizin[Grad-verleihende Institution]
	1029510660

Zusammenfassung:

Stem cell therapy holds great promise in the treatment of cardiac disease. A major limitation to the efficacy of cell therapy is the poor viability of the transplanted cells. Our present studies revealed that genetic modification of MSCs effectively protects transplanted MSCs against ischemia and increases cell survival after implantation. Continued development and application of genetic manipulation approaches in stem cells will undoubtedly lead to more efficient guidance and control of stem cell fate and improved stem cell function. [Englisch]

Dokumenttyp:

Habilitationsschrift

Einrichtung:

Universitätsmedizin

Sprache:

Englisch

Sachgruppe der DNB:

610 Medizin, Gesundheit

Veröffentlichung /
Entstehung:

Rostock

Rostock: Universität Rostock

2009