Synthesis of Functionalized Quinolines, Flavones, Coumarins, Naphthoates and Phthalates by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions

Nadi Fakhry Eleya

doi:10.18453/rosdok_id00001028

Nadi Fakhry Eleya

Synthesis of Functionalized Quinolines, Flavones, Coumarins, Naphthoates and Phthalates by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions

Universität Rostock, 2012

https://doi.org/10.18453/rosdok_id00001028

Abstract: This thesis includes regioselective palladium(0)-catalyzed Suzuki cross-coupling reactions of quinolines, flavones, coumarins, naphthaoates and phthalates. Suzuki cross-coupling reaction of 5,7-dibromo-8-(trifluoromethanesulfonyloxy)quinoline afforded arylated quinolines.The Suzuki reaction of the bis(triflates)of 5,7-dihydroxyflavone,4-methyl-5,7-dihydroxycoumarin,4-methyl-5,8-dihydroxycoumarin, ethyl 3,5-dihydroxy-2-naphthaoate and methyl 3,7-dihydroxy-2-naphthoate gave the corresponding arylated derivatives. The reaction of tetrabromophthalate with boronic acids gave tetraarylphthalates.

Dissertation Freier Zugang

Titel:

Synthesis of Functionalized Quinolines, Flavones, Coumarins, Naphthoates and Phthalates by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions

Beteiligte Personen:

Nadi Fakhry Eleya[VerfasserIn]
	1025628063
Wolfgang Maison , Prof. Dr.[AkademischeR BetreuerIn]
Peter Langer , Prof. Dr.[AkademischeR BetreuerIn]

Beteiligte Körperschaften:

Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution]
	2147083-2

Zusammenfassung:

This thesis includes regioselective palladium(0)-catalyzed Suzuki cross-coupling reactions of quinolines, flavones, coumarins, naphthaoates and phthalates. Suzuki cross-coupling reaction of 5,7-dibromo-8-(trifluoromethanesulfonyloxy)quinoline afforded arylated quinolines.The Suzuki reaction of the bis(triflates)of 5,7-dihydroxyflavone,4-methyl-5,7-dihydroxycoumarin,4-methyl-5,8-dihydroxycoumarin, ethyl 3,5-dihydroxy-2-naphthaoate and methyl 3,7-dihydroxy-2-naphthoate gave the corresponding arylated derivatives. The reaction of tetrabromophthalate with boronic acids gave tetraarylphthalates. [Englisch]

Dokumenttyp:

Dissertation

Einrichtung:

Mathematisch-Naturwissenschaftliche Fakultät

Sprache:

Englisch

Sachgruppe der DNB:

540 Chemie

Veröffentlichung /
Entstehung:

Rostock

Rostock: Universität Rostock

2012