| title: |
| Routes to polysubstituted and condensed pyridines and diazines - utilization of 1,3-bielectrophiles
and transition metal-based catalysis in ring synthesis/modification |
|
| contributing persons: |
| Dmytro Ostrovskyi[VerfasserIn] |
 |
1029568480 |
| Peter Langer
, Prof. Dr.[AkademischeR BetreuerIn] |
| Till Opatz
, Prof. Dr.[AkademischeR BetreuerIn] |
|
| contributing corporate bodies: |
| Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
|
| |
| abstract: |
|
The present work aimed to study the potential of well-known synthetic strategies for
the synthesis of imidazo[4,5-b]pyridine-derived (or 1-desazapurine-derived), purine-derived
and benzimidazole-derived moieties and their modifications. This includes [3+3] cyclocondensations,
inverse electron-demand Diels-Alder reaction, intramolecular palladium-catalyzed arylation.
In addition, unprecedented method of synthesis of 4-trifluoromethylpyridines was developed,
including scope limitation and theoretical mechanistic studies with DFT methods.
[English] |
|
Die vorliegende Arbeit untersucht das Potential bekannter Synthesestrategien zum Aufbau
von Derivaten des Imidazo[4,5-b]pyridins (1-Desazapurin), Purins und Benzimidazols.
Dies beinhaltet [3+3] Zyklokondensationen, Inverse Diels-Alder Reaktionen sowie intramolekulare
Palladium katalysierte Arylierungen. Außerdem wurde eine neue Methode für die Synthese
von 4-Trifluoromethylpyridinen entwickelt, einschließlich der Eingrenzung der Anwendbarkeit
und theoretischen mechanistischen Untersuchungen mittels DFT.
[German] |
|
| document type: |
|
| institution: |
| Faculty of Mathematics and Natural Sciences |
|
| language: |
|
| subject class (DDC): |
| 540 Chemistry & allied sciences |
|
| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2012
|
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| |
| identifiers: |
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| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000000916 |
| created / modified: |
11.01.2013 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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