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Muhammad Zahid

Synthesis and characterization of Benzo-[1,8]-naphthyridine-4(1H)-ones, Benzo[b]pyrazolo-[5,1-f][1,6]-naphthyridines, Benzo-[4',5']-imidazo-[1',2':1,2]-pyrido-[4,3-b]indoles and fluorinated arenes

Universität Rostock, 2012

Abstract: Domino amination/conjugate addition reactions have been used to synthesize a new class of 4-quinolones. An efficient route for the synthesis of benzo[b]pyrazolo[5,1-f][1,6]naphthyridines via silver triflate-catalyzed one-pot tandem reactions has also been developed which proceeds with good functional group tolerance under mild conditions with high efficiency and excellent selectivity. A high yielding route for the synthesis of fluorinated arenes, which are difficult to obtain, has been developed by direct acyl-alkylation of benzyne.

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