goto contents

Doreen Staar

Einfluss von 17β-Estradiol und Genistein auf kultivierte vaskuläre glatte Muskel- und Endothelzellen und Charakterisierung von Gewebereaktionen auf 17β-Estradiol- und Genistein-Eluting Stents in porcinen, kultivierten Carotisabschnitten

Universität Rostock, 2013

Abstract: The percutaneous coronary intervention with implantation of a stent is the preferred method for the treatment of cardiovascular diseases. The aim is the further development of drug-eluting stents that significantly reduce the rate of restenosis. In this work 17β-estradiol and genistein were examined for the effect on vascular cells and cultured blood vessels. At the cellular and tissue level 17β-estradiol provides no cardio protective properties. The local release of genistein can improve the vascular healing response. It represents an option in the development of new drug-eluting stents.

doctoral thesis   free access    


OPACGVKDataCite Commons


all rights reserved

This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz).