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Martin Jacobsen

Detektion organischer Moleküle mit Hilfe von heizbaren Elektroden im negativen Potentialbereich

Universität Rostock, 2013

https://doi.org/10.18453/rosdok_id00001247

Abstract: For a bigger commensurable potential range we used directly heatable bismuth electrodes. With these electrodes it was possible to measure in a more negative potential. We could detect a very small amount of organic molecules. Furthermore we could detect hybridization reactions on heated gold electrodes. We used targed strands labeled with the complex [OsO4(bipy] and detect them on immobilized probes. It was possible to label DNA and RNA-strands. The use of higher temperatures enabled the separation of complementary DNA-targets and targets containing mismatches.

doctoral thesis   free access