title: |
Improved synthesis of 2,3-diacetamidouronates which are present in bacterial envelope |
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contributing persons: |
Jaya Shanmuga Prakash Jegannathan[VerfasserIn] |
 |
1046201883 |
Christian Vogel
, Prof. Dr.[AkademischeR BetreuerIn] |
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1011717204 |
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University of Rostock, Institute of Organic Chemistry |
Till Opatz
, Prof. Dr.[AkademischeR BetreuerIn] |
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122688511 |
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University of Mainz, Institute of Organic Chemistry |
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contributing corporate bodies: |
Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
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2147083-2 |
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abstract: |
Diacetamidodideoxyuronic acids are components of lipopolysaccarides present in bacterial
cell wall. There are very few publications reporting the preparation of this class
of sugars. Hence, we present the synthesis of gluco-, galacto- and manno- configured
sugars of 2,3-diacetamido-2,3-dideoxy-D-uronates. These monosaccharaides can be employed
as glycosyl donors and acceptors in glycosylation reactions to produce larger glycosylates
which can serve as components of antibiotics. Currently, the target molecules were
synthesized in high yields with good reproducibility and scalability.
[English] |
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document type: |
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institution: |
Faculty of Mathematics and Natural Sciences |
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language: |
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subject class (DDC): |
540 Chemistry & allied sciences |
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publication / production: |
Rostock: Universität Rostock
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2014
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000001074 |
created / modified: |
10.01.2014 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |