Universität Rostock, 2014
Abstract: First toxicity and pH-value were investigated. Based on this results ionic liquids were chosen for a new application in medical engineering. Cetylpyridiniumsalicylate was selected for a coating of balloons for percutane coronar intervention (PCI). Paclitaxel, the used drug, is dissolved excellently in the IL. The coating is smooth. The ionic liquid also has exceptional behavior regarding melting. A solution of water and ionic liquid shows thixotropic characteristics. Moreover a process for heat treatment was investigated and improved by using ionic liquids.
doctoral thesis free access