Analysis of the FGF signalling pathway during embryogenesis of the red flour beetle Tribolium castaneum

Rahul Sharma

doi:10.18453/rosdok_id00001387

Rahul Sharma

Analysis of the FGF signalling pathway during embryogenesis of the red flour beetle Tribolium castaneum

Universität Rostock, 2014

https://doi.org/10.18453/rosdok_id00001387

Abstract: FGF signalling is vital for early development in vertebrates and invertebrates. I studied the function of various FGF signalling components during embryogenesis of the beetle Tribolium castaneum. I found that Fgf1b, which is absent in Drosophila, is crucial for organising the early anterior fate of the beetle along the AP-axis. I further show that, like in Drosophila, Fgf8 in Tribolium is critical for mesoderm morphogenesis. However, unlike Drosophila, the single FGF-receptor in Tribolium integrates with both the ligands Fgf8 and Branchless during mesoderm and tracheal formation respectively.

Dissertation Freier Zugang

Titel:

Analysis of the FGF signalling pathway during embryogenesis of the red flour beetle Tribolium castaneum

Beteiligte Personen:

Rahul Sharma[VerfasserIn]
	1057855456
Reinhard Schröder , Prof. Dr. rer. nat.[AkademischeR BetreuerIn]
	143434314
	Universität Rostock, Institut für Biowissenschaften, Abteilung Genetik
Manfred Frasch , Prof. Dr. rer. nat.[AkademischeR BetreuerIn]
	Friedrich-Alexander-Universität Erlangen-Nürnberg, Lehrstuhl für Entwicklungsbiologie

Beteiligte Körperschaften:

Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution]
	2147083-2

Zusammenfassung:

FGF signalling is vital for early development in vertebrates and invertebrates. I studied the function of various FGF signalling components during embryogenesis of the beetle Tribolium castaneum. I found that Fgf1b, which is absent in Drosophila, is crucial for organising the early anterior fate of the beetle along the AP-axis. I further show that, like in Drosophila, Fgf8 in Tribolium is critical for mesoderm morphogenesis. However, unlike Drosophila, the single FGF-receptor in Tribolium integrates with both the ligands Fgf8 and Branchless during mesoderm and tracheal formation respectively. [Englisch]

Dokumenttyp:

Dissertation

Einrichtung:

Mathematisch-Naturwissenschaftliche Fakultät

Sprache:

Englisch

Sachgruppe der DNB:

570 Biowissenschaften, Biologie

Veröffentlichung /
Entstehung:

Rostock

Rostock: Universität Rostock

2014