title: |
MicroRNA and messengerRNA expression changes during interferon-beta and glatiramer
acetate treatment in peripheral blood cells of multiple sclerosis patients |
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contributing persons: |
Madhan Thamilarasan[VerfasserIn] |
 |
1071833413 |
Uwe Zettl
, Prof. Dr. med.[AkademischeR BetreuerIn] |
 |
120760819 |
|
University of Rostock, Department of Neurology |
Friedemann Paul
, Prof. Dr. med.[AkademischeR BetreuerIn] |
|
Charité, Berlin, NeuroCure Clinical Research Center |
Jürgen Faiss
, Dr. med.[AkademischeR BetreuerIn] |
|
Asklepios Klinikum Teupitz, Department of Neurology |
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contributing corporate bodies: |
Universität Rostock, Universitätsmedizin[Grad-verleihende Institution] |
 |
1029510660 |
|
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abstract: |
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system.
There are many types of disease-modifying drugs available but none of them can cure
MS. The studies reported in this thesis analyzed the changes which happen at the transcriptome
level during the course of treatment with glatiramer acetate (GA) and interferon-beta-1b.
The studies reported revealed several differentially expressed transcripts which included
both mRNAs and microRNAs. These can be considered as biomarkers for therapy monitoring
and help to better understand the mechanisms of action of the drugs.
[English] |
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document type: |
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institution: |
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language: |
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subject class (DDC): |
610 Medical sciences Medicine |
570 Life science |
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publication / production: |
Rostock: Universität Rostock
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2015
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000001369 |
created / modified: |
08.06.2015 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |