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Jenny Bandomir

Development and characterization of hydrogels and their use in in-vitro studies of drug-coated balloons

Universität Rostock, 2015


Abstract: This thesis summarizes the development and characterization of novel hydrogels based on polymerized ionic liquids. The mechanical characterization by tensile and compression tests was mainly performed using various parameters influencing the stability. In addition, a comparison with well-known hydrogels was made. These materials were used as artificial vessel model to carry out balloon dilations. By use of a flow-through cell, an artificial vessel wall could be generated. The drug release of drug-coated balloon catheters was characterized in detail.

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