3-Substituted chromones as convenient building blocks for the design and synthesis of functionalized 2-hydroxybenzophenones, 6H-benzo[c]chromenes, benzo[c]coumarins, fused pyridine derivatives, 2-salicyloylfurans and 2-benzoyl-8H-thieno[2,3-b]indoles

Iryna Savych

doi:10.18453/rosdok_id00001746

Iryna Savych

3-Substituted chromones as convenient building blocks for the design and synthesis of functionalized 2-hydroxybenzophenones, 6H-benzo[c]chromenes, benzo[c]coumarins, fused pyridine derivatives, 2-salicyloylfurans and 2-benzoyl-8H-thieno[2,3-b]indoles

Universität Rostock, 2016

https://doi.org/10.18453/rosdok_id00001746

Abstract: The present thesis is dedicated to the study of synthetic potential of 3-substituted chromones, namely 3-acyl- and 3-halochromones, illustrated by regioselective cyclocondensation reactions with different binucleophiles and describes the design and synthesis of novel biologically relevant carbo- and heterocycles. Various fluorine-containing products were synthesized using 3-perfluoroacylchromones. In addition, new promising candidates for UV-A/B filters and fluorescent compounds have been synthesized and analyzed.

doctoral thesis free access

title:

3-Substituted chromones as convenient building blocks for the design and synthesis of functionalized 2-hydroxybenzophenones, 6H-benzo[c]chromenes, benzo[c]coumarins, fused pyridine derivatives, 2-salicyloylfurans and 2-benzoyl-8H-thieno[2,3-b]indoles

contributing persons:

Iryna Savych[VerfasserIn]
	1072022893
Peter Langer , Prof. Dr. Dr. h. c. mult.[AkademischeR BetreuerIn]
	132314614
	Universität Rostock, Institut für Chemie
Thomas J. J. Müller , Prof. Dr.[AkademischeR BetreuerIn]
	11370979X
	Heinrich-Heine-Universität Düsseldorf, Institut für Organische und Makromolekulare Chemie

contributing corporate bodies:

Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution]
	2147083-2

abstract:

The present thesis is dedicated to the study of synthetic potential of 3-substituted chromones, namely 3-acyl- and 3-halochromones, illustrated by regioselective cyclocondensation reactions with different binucleophiles and describes the design and synthesis of novel biologically relevant carbo- and heterocycles. Various fluorine-containing products were synthesized using 3-perfluoroacylchromones. In addition, new promising candidates for UV-A/B filters and fluorescent compounds have been synthesized and analyzed. [English]

Die vorliegende Arbeit beschreibt das synthetische Potential von 3-Substituierten Chromonen, nämlich 3-Acyl- und 3-Halogenchromonen, durch Dominoreaktionen mit verschiedenen Dinukleophilien und ist dem Design und der Synthese von neuartigen biologisch relevanten Carbo- und Heterocyclen gewidmet. Verschiedene fluorierte Produkte wurden durch den Gebrauch von 3-Fluoroacylchromonen hergestellt. Einige synthetisierte Substanzen zeigen vielversprechende Absorption- und Fluoreszenzeigenschaften. [German]

document type:

doctoral thesis

institution:

Faculty of Mathematics and Natural Sciences

language:

English

subject class (DDC):

540 Chemistry & allied sciences

publication /
production:

Rostock: Universität Rostock

2016

identifiers: