title: |
Identification and characterization of CD4+AT2R+ T cell subpopulation in humans and
rats |
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other title: |
Identifizierung und Charakterisierung der CD4+AT2R+ T Zell Subpopulation bei Mensch
und Ratte
[translated]
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contributing persons: |
Anna Skorska[VerfasserIn] |
|
1105676196 |
Gustav Steinhoff
, Prof. Dr. med.[AkademischeR BetreuerIn] |
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136129560 |
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Rostock University Medical Center, Clinic and Policlinic for Cardiac Surgery |
Brigitte Vollmar
, Prof. Dr. med.[AkademischeR BetreuerIn] |
|
136319564 |
|
Rostock University Medical Center, Institute for Experimental Surgery |
Hans-Dieter Volk
, Prof. Dr. med.[AkademischeR BetreuerIn] |
|
Charité – Universitätsmedizin Berlin, Institute of Medical Immunology; Berlin-Brandenburger
Center for Regenerative Therapies (BCRT) |
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contributing corporate bodies: |
Universität Rostock, Universitätsmedizin[Grad-verleihende Institution] |
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1029510660 |
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abstract: |
The study contributes to the understanding of CD4+AT2R+ cell function after myocardial
infarction (MI). This potential novel T cell subset, which expresses FoxP3 and various
cytokines improves cardiac function and reduces infarct size. Results indicate that
the CD4+AT2R+ T cells might be included in therapeutic approaches for the treatment
of cardiac diseases, due to its upregulation in the infarcted state. The application
of this T cell subset may improve the healing process of compromised heart tissue
and contribute to a better quality of life in affected patients.
[English] |
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document type: |
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institution: |
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language: |
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subject class (DDC): |
610 Medical sciences Medicine |
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publication / production: |
Rostock
Rostock: Universität Rostock
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2016
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000001585 |
created / modified: |
05.07.2016 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |