title: |
Caveolae-mediated phagocytosis of biomaterial surface structures by human osteoblasts |
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contributing persons: |
Caroline Mörke[VerfasserIn] |
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1111521808 |
Barbara Nebe
, Prof. Dr.[AkademischeR BetreuerIn] |
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172943744 |
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Universitätsmedizin Rostock, Zentrum für Medizinische Forschung, Arbeitsbereich Zellbiologie |
Sergei A. Kuznetsov
, PD Dr.[AkademischeR BetreuerIn] |
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Universität Rostock, Institut für Biowissenschaften, Abteilung Tierphysiologie |
Jan de Boer
, Prof. Dr.[AkademischeR BetreuerIn] |
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University of Twente, Institute for Biomedical Technology and Technical Medicine |
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contributing corporate bodies: |
Universität Rostock, Universitätsmedizin[Grad-verleihende Institution] |
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1029510660 |
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abstract: |
Cells are sensitive to their underlying topography, which evoke large ranges of cell
responses. The work describes an attempted caveolae-mediated phagocytosis of the surface-fixed
micro-pillars by human MG-63 osteoblastic cells. This attempt to phagocytize the elevations
of the Ti surface results in higher energy requirements for the cells and finally
to impaired osteoblast function. Similar cell responses were observed for the osteoblasts
treated with micro-particles as phagocytosis trigger and osteoblasts growing on stochastic
rough Ti surfaces, commercially used as implant surfaces.
[English] |
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document type: |
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institution: |
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language: |
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subject class (DDC): |
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publication / production: |
Rostock
Rostock: Universität Rostock
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2016
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000001607 |
created / modified: |
12.08.2016 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |