| title: |
| Oral bacteria, stem cells and neutrophils in vitro: a model for periodontal infection |
|
| contributing persons: |
| Cathleen Hieke[VerfasserIn] |
 |
1136984550 |
| Bernd Kreikemeyer
, Prof. Dr. rer. nat.[AkademischeR BetreuerIn] |
|
114684618 |
|
Universität Rostock, Institut für Mikrobiologie, Virologie und Hygiene |
| Hubert Bahl
, Prof. Dr. rer. nat.[AkademischeR BetreuerIn] |
|
132475170 |
|
Universität Rostock, Institut für Mikrobiologie, Virologie und Hygiene |
|
| contributing corporate bodies: |
| Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
|
| |
| abstract: |
|
Periodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms.
Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear
neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions
between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis,
human dental stem cells (hDFSCs) and PMNs. HDFSCs modulate immune activity of PMNs
after infection with oral bacteria implying general suitability of hDFSCs in tissue
regeneration strategies after tissue damage in periodontal infections.
[English] |
|
| document type: |
|
| institution: |
| Faculty of Mathematics and Natural Sciences |
|
| language: |
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| subject class (DDC): |
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| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2017
|
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000001763 |
| created / modified: |
19.07.2017 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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