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Anne-Marie Galow

Optimierung von in vitro Kultursystemen für Knochenzellen : Einfluss von pH und mechanischer Stimulation

Universität Rostock, 2018

Abstract: Experiments at different medium pH showed positive effects on the proliferation and differentiation of osteoblasts for alkaline pH values. Based on this findings, initial approaches to an in vitro model system for an implant that alkalizes the microenvironment were accomplished. In another model system, a significant positive effect on the proliferation of the upper osteoblasts could be observed when mechanically stimulating the lower osteocyte population in co-culture while no significant effects were observed when osteoblasts were used as stimulated populations.

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