goto contents


Susanne Thümecke

Die Rolle des Gens flipflop in der frühen Morphogenese des Mehlkäfers Tribolium castaneum

Universität Rostock, 2018

https://doi.org/10.18453/rosdok_id00002048

Abstract: Tribolium develops everted limb buds during embryogenesis. However, the molecular mechanisms directing this process are only poorly understood. Here I show that the newly discovered genes flipflop1 and flipflop2 are involved in regulating the direction of budding. RNA interference-knockdown of the flipflop genes causes embryonic limb buds to grow inwards rather than evert, leading to the development of fully differentiated appendages inside the larval body. The identification of additional candidate genes places the flipflop genes within Rho-dependent signalling pathways.

doctoral thesis   free access    


Portals

OPACGVKDataCite Commons

Rights

all rights reserved

This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz).