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Silvio Parpart

Synthese polycyclischer aromatischer Stickstoff-Heterocyclen : Verwendung von Palladium-katalysierten Kupplungsreaktionen und Lewis-Säure vermittelter Cycloisomerisierung

Universität Rostock, 2018

Abstract: The present thesis deals with the synthesis of thieno[3,2-b]indoles, pyrrolo[1,2-a][1,8]naphthyridines, pyrrolo[1,2-a][1,6]naphthyridines as well as indolizino[6,5,4,3-ija][1,6]naphthyridines. All starting materials are easy available building-blocks. To prepare the polycyclic compounds, especially palladium-catalyzed cross-coupling reactions (Suzuki reaction, Sonogashira reaction, Buchwald-Hartwig amination) and cycloisomerization reactions (ring-closing alkyne-carbonyl-metathesis, intramolecular electrophilic aromatic substitution) were used.

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