title: |
Unraveling the regulatory mechanisms controlling the biosynthesis and emission of
the volatile organic compound ’sodorifen’ produced by Serratia plymuthica 4Rx13 |
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contributing persons: |
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contributing corporate bodies: |
Universität Rostock[Grad-verleihende Institution] |
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38329-6 |
Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
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2147083-2 |
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abstract: |
The aim of this work was to investigate the regulatory mechanisms underlying production
of the unique volatile compound sodorifen in different Serratia species. For this
purpose, expression analyses of the biosynthetic gene cluster were performed and global
regulatory pathways in the sodorifen producing strain S. plymuthica 4Rx13 inactivated.
As a result, biosynthesis of sodorifen was found to be predominantly regulated on
a transcriptional level and the obtained results gave rise to the speculation that
it might be involved in stress response of the producing bacteria.
[English] |
Ziel der Arbeit war es, die Regulation der ungewöhnlichen, volatilen Verbindung Sodorifen
in verschiedenen Serratia Spezies zu untersuchen. Zu diesem Zweck wurden Expressionsanalysen
des entsprechenden Biosynthese-Genclusters durchgeführt und zentrale Regulationsmechanismen
im Sodorifen-Produzenten Serratia plymuthica 4Rx13 mittels Mutagenese inaktiviert.
Dabei zeigte sich, dass die Biosynthese dieser ungewöhnlichen volatilen Verbindung
hauptsächlich transkriptionell reguliert ist und dass Sodorifen eine mögliche Rolle
in der Stress-Antwort der produzierenden Bakterien spielt.
[German] |
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document type: |
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institution: |
Faculty of Mathematics and Natural Sciences |
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language: |
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subject class (DDC): |
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publication / production: |
Rostock
Rostock: Universität Rostock
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2018
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statement of responsibility: |
vorgelegt von Nancy Magnus |
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000001985 |
created / modified: |
02.11.2018 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |