| title: |
| Synthesis of novel quinolines, pyrrolo[2,3-b]indoles, and 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-diones
via palladium-catalyzed cross-coupling reactions |
|
| contributing persons: |
|
| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
 |
38329-6 |
| Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
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| |
| abstract: |
|
The present thesis is mainly dedicated to the study of the synthesis of quinolines,
pyrolo[2,3-b]indoles and 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-diones via palladium-catalyzed
cross-coupling reactions. This includes arylation of quinolines via Suzuki-Miyaura
and alkynylation of 4-trifluoromethylquinolines via Sonogashira reaction. Consequent
synthesis of a wide range of fused pyridines and their further modifications were
successfully performed. A number of pyrolo[2,3-b]indoles and pyrimido[4,5-b]indole-2,4(3H,9H)-diones
were synthesized with the usage of Buchwald-Hartwig reaction.
[English] |
|
Die vorliegende Arbeit beschäftigt sich mit der Synthese von Chinolinen, Pyrolo[2,3-b]indolen
und 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dionen durch Palladium-katalysierte Kreuzkupplungsreaktionen.
Sie beinhaltet Arylierungen von Chinolinen mittels Suzuki-Miyaura-Reaktion und Alkinylierung
von 4-Trifluoromethylchinolinen mittels Sonogashira-Reaktion. Außerdem wurden verschiedene
Pyrolo[2,3-b]indole und Pyrimido[4,5-b]indole-2,4(3H,9H)-dione durch Buchwald-Hartwig-Reaktion
hergestellt.
[German] |
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| document type: |
|
| institution: |
| Faculty of Mathematics and Natural Sciences |
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| language: |
|
| subject class (DDC): |
| 540 Chemistry & allied sciences |
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| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2017
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|
| statement of responsibility: |
| vorgelegt von M. Sc. Maksym Cherevatenko |
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| |
| identifiers: |
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| access condition: |
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| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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|
| RosDok id: |
rosdok_disshab_0000002064 |
| created / modified: |
15.02.2019 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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