goto contents


Rodisnel Perdomo Rivera

Synthesis of functionalized pyridines and quinolines by palladium-catalyzed cross-coupling reactions

Universität Rostock, 2018

https://doi.org/10.18453/rosdok_id00002513

Abstract: This thesis deals with the functionalization of pentahalogenated pyridines and dihalogenated quinolines through palladium catalyzed cross coupling reactions. This includes the chemo-selective arylation and alkynylation of 4-bromo-2,3,5-trichloro-6-iodopyridine using Suzuki and Sonogashira reactions. The chemo-selective arylation of 4,6-dihalogenated-2-(trifluoromethyl)quinoline by Suzuki reaction was studied. Besides, the synthesis of indolo [2,3-c]quinolines was studied by sequential chemo-selective Suzuki reaction followed by double C-N coupling starting from 3-bromo-4-iodoquinoline.

doctoral thesis   free access    


Portals

OPACGVKDataCite Commons

Rights

all rights reserved

This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz).