title: |
Der Aldosteron-/Renin- und Kalium-Quotient im Vergleich zum Aldosteron-/Renin-Quotient
in der Diagnostik des Conn-Syndroms |
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contributing persons: |
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contributing corporate bodies: |
Universität Rostock[Grad-verleihende Institution] |
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38329-6 |
Universitätsmedizin Rostock[Grad-verleihende Institution] |
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1029510660 |
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abstract: |
Der Aldosteron/Renin-Quotient (ARQ) ist die derzeitige Standardscreeningmethode des
Primären Aldosteronismus (PA). Ziel der Arbeit war es zu überprüfen, ob eine Integration
vom Serumkaliumwert in den ARQ, der ARK, den Screeningprozess verbessert. Im Rahmen
des Conn Registers und der SHIP-PAGE-Studie wurden retrospektiv Daten von essentiellen
Hypertonikern und Conn-Patienten analysiert. Die Receiver operating curves erbrachten
größere Flächen untern den Kurven für den ARK als für den ARQ. Der ARK kann als Screeninginstrument
genutzt werden und vereinfacht den Screeningprozess.
[German] |
The aldosterone to renin ratio (ARR) is a widely employed screening tool for primary
aldosteronism (PA). We asked if correcting the ARR for serum potassium values (ARP)
renders a better screening test. The German Conn registry and the SHIP-PAGE study
were used to retrospectively analyze data of hypertensive patients who underwent investigation
for suspected primary aldosteronism. All receiver-operating curves for the ARP had
a higher area under the curve than for the ARR. This study indicates that the ARP
can be used as well as the ARR and may improve or ease the screening process.
[English] |
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document type: |
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institution: |
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language: |
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subject class (DDC): |
610 Medical sciences Medicine |
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publication / production: |
Rostock: Universität Rostock
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2019
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statement of responsibility: |
vorgelegt von Ulrike Heise |
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000002163 |
created / modified: |
15.08.2019 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |