| title: |
| Antiarrhythmic effect of human bone marrow-dereived CD271+ mesenchymal stem cells
tested in vivo using a new infarction-re-infarction mouse model |
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| contributing persons: |
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| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
 |
38329-6 |
| Universitätsmedizin Rostock[Grad-verleihende Institution] |
|
1029510660 |
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| abstract: |
|
This experiment showed the safety and antiarrhythmic effect of human bone marrow-derived
CD271+ MSC. This was performed in immune deficient mice (Rag2-/-γc-/--mice) with electrocardiogram
monitoring through Implantation of telemtry system. The induction of ventricular arrhythmias
has been achieved via a permanent re-infarction through left anterior descending artery
(LAD) ligation one week after a 30-minute ischemia-reperfusion. The time between 2
infarctions gave the stem cells the required period to entgraft themselves after their
intramyocardial injection with the first infarction.
[English] |
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| document type: |
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| institution: |
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| language: |
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| subject class (DDC): |
| 610 Medical sciences Medicine |
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publication /
production: |
Rostock
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Rostock: Universität Rostock
|
|
2019
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|
| statement of responsibility: |
| vorgelegt von Haval Lutfalla Sadraddin |
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| identifiers: |
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| access condition: |
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| license/rights statement: |
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| RosDok id: |
rosdok_disshab_0000002469 |
| created / modified: |
04.03.2021 / 08.08.2023
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| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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