| title: |
| Identification of the microsatellite stability status and inhibitor of NF-kappa-B
expression levels as biomarkers to predict sensitivity to pharmaceutical curcumin
in colorectal cancer cells |
|
| contributing persons: |
| Lili Lu[VerfasserIn] |
 |
0000-0001-6638-624X |
 |
1241495157 |
| Michael Linnebacher[AkademischeR BetreuerIn] |
|
0000-0001-8054-1402 |
|
1028873808 |
|
Molekulare Onkologie und Immuntherapie, Allgemeine Chirurgie, Universitätsmedizin
Rostock |
| Robert Georg Ramer[AkademischeR BetreuerIn] |
|
129973092 |
| Oliver H. Krämer[AkademischeR BetreuerIn] |
|
Institut für Toxikologie, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz |
|
| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
|
38329-6 |
| Universitätsmedizin Rostock[Grad-verleihende Institution] |
|
1029510660 |
|
| |
| abstract: |
|
The present study aimed at 1) testing the sensitivity of CRC cell lines with defined
molecular alterations to curcumin; 2) mechanistically analyzing sensitive CRC cell
lines in order to identify the mode-of-action; 3) identifying biomarkers associated
with curcumin sensitivity; 4) establishing a predictive model using biomarkers to
predict the sensitivity of additional CRC cell line to curcumin.
[English] |
|
| document type: |
|
| institution: |
|
| language: |
|
| subject class (DDC): |
| 500 Natural sciences |
| 610 Medical sciences Medicine |
|
| |
publication /
production: |
|
Rostock: Universität Rostock
|
|
2021
|
|
| statement of responsibility: |
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000002583 |
| created / modified: |
20.09.2021 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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