title: |
Identification of the microsatellite stability status and inhibitor of NF-kappa-B
expression levels as biomarkers to predict sensitivity to pharmaceutical curcumin
in colorectal cancer cells |
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contributing persons: |
Lili Lu[VerfasserIn] |
|
0000-0001-6638-624X |
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1241495157 |
Michael Linnebacher[AkademischeR BetreuerIn] |
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0000-0001-8054-1402 |
|
1028873808 |
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Molekulare Onkologie und Immuntherapie, Allgemeine Chirurgie, Universitätsmedizin
Rostock |
Robert Georg Ramer[AkademischeR BetreuerIn] |
|
129973092 |
Oliver H. Krämer[AkademischeR BetreuerIn] |
|
Institut für Toxikologie, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz |
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contributing corporate bodies: |
Universität Rostock[Grad-verleihende Institution] |
|
38329-6 |
Universitätsmedizin Rostock[Grad-verleihende Institution] |
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1029510660 |
|
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abstract: |
The present study aimed at 1) testing the sensitivity of CRC cell lines with defined
molecular alterations to curcumin; 2) mechanistically analyzing sensitive CRC cell
lines in order to identify the mode-of-action; 3) identifying biomarkers associated
with curcumin sensitivity; 4) establishing a predictive model using biomarkers to
predict the sensitivity of additional CRC cell line to curcumin.
[English] |
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document type: |
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institution: |
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language: |
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subject class (DDC): |
500 Natural sciences |
610 Medical sciences Medicine |
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publication / production: |
Rostock
Rostock: Universität Rostock
|
2021
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statement of responsibility: |
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identifiers: |
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access condition: |
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license/rights statement: |
all rights reserved This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
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RosDok id: |
rosdok_disshab_0000002583 |
created / modified: |
20.09.2021 / 08.08.2023
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metadata license: |
The metadata of this document was dedicated to the public domain (CC0 1.0 Universal Public Domain Dedication). |