Development of 3d metal catalysts for redox reactions

David Leonard

doi:10.18453/rosdok_id00003492

David Leonard

Development of 3d metal catalysts for redox reactions

Universität Rostock, 2021

https://doi.org/10.18453/rosdok_id00003492

Abstract: Herein is reported the application of non-noble metal-based catalytic systems for the homogeneous oxidation of organic substrates using air, specifically in amines and N-heterocycles. Simple 3d metal salts have been used, in combination with N-ligands, to facilitate the oxidative cleavage of C(sp3)–C(sp3) bonds. These reactions have been studied, using spectroscopic methods, to propose plausible mechanistic pathways. We believe such deconstructive strategies can enable late-stage functionalisation of pharmaceuticals and the synthesis of drug metabolites.

Dissertation Freier Zugang

Titel:

Development of 3d metal catalysts for redox reactions

Beteiligte Personen:

David Leonard[VerfasserIn]
	0000-0002-3471-2060
	1251957994
Matthias Beller[AkademischeR BetreuerIn]
	0000-0001-5709-0965
	112081908
	Leibniz Institute for Catalysis
Shoubhik Das[AkademischeR BetreuerIn]
	0000-0002-4577-438X
	1018978429
	University of Antwerp

Beteiligte Körperschaften:

Universität Rostock[Grad-verleihende Institution]
	38329-6
Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution]
	2147083-2

Zusammenfassung:

Herein is reported the application of non-noble metal-based catalytic systems for the homogeneous oxidation of organic substrates using air, specifically in amines and N-heterocycles. Simple 3d metal salts have been used, in combination with N-ligands, to facilitate the oxidative cleavage of C(sp3)–C(sp3) bonds. These reactions have been studied, using spectroscopic methods, to propose plausible mechanistic pathways. We believe such deconstructive strategies can enable late-stage functionalisation of pharmaceuticals and the synthesis of drug metabolites. [Englisch]

Dokumenttyp:

Dissertation

Einrichtung:

Mathematisch-Naturwissenschaftliche Fakultät

Sprache:

Englisch

Sachgruppe der DNB:

500 Naturwissenschaften

540 Chemie

Veröffentlichung /
Entstehung:

Rostock: Universität Rostock

2021