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Xin Cao

Investigation of the impact of three different reference particulate matter on human monocytic THP-1 and lung epithelial A549 cells

Universität Rostock, 2021

Abstract: Air pollution has been one of the biggest environmental issues in the world. Particulate matter (PM) is a very important component of air pollutants. In this thesis, we firstly found PM, collected from different districts, contained diverse PAHs, and exhibited different toxic and mutagenic equivalent. To understand how PM from different sources impact cells and which components play a key role in the observed adverse effects, in vitro experiments on distinct cell types were conducted.

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