Universität Rostock, 2022
Abstract: This dissertation deals with the synthesis of small molecules for use in skin cancers with possible plasma application. First, N-glycosylated oxindoles and N-glycosylated isatins bearing electron-withdrawing substituents were synthesized. Furthermore, highly functionalized synthetic building blocks were synthesized in regio- and chemo selective palladium-catalyzed coupling reactions with various boronic acids and alkynes, which then reacted to form heterocycles by acid-mediated cycloisomerization or alkyne-carbonyl metathesis.
doctoral thesis free access