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Marcel Kordt

In vivo Charakterisierung der antitumorigenen Effizienz von kaltem Atmosphärendruckplasma und small molecules am Modell des menschlichen Hautkrebses

Universität Rostock, 2022

https://doi.org/10.18453/rosdok_id00004440

Abstract: Skin cancer is one of the most common cancers worldwide. In this dissertation, the promising anticarcinogenic effect of cold atmospheric pressure plasma (CAP) against skin cancer was investigated in vivo. KAP reduced tumour growth and increased reactive species, but did not affect apoptosis or metabolism in the tumour. KAP in combination with small molecules showed synergistic anticarcinogenic effects with reduced tumour growth. These results suggest that KAP may be a promising option for the treatment of skin cancer.

doctoral thesis   free access