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Franziska Juliane Zessin

Video-EEG-Analysen von Gliom-tragenden Ratten unter Behandlung mit Perampanel

Universität Rostock, 2023

https://doi.org/10.18453/rosdok_id00004510

Abstract: The effectiveness of the AMPA receptor blocker perampanel in the treatment of glioma patients was examined in an animal experiment. For this purpose, gliomas were grown by cell injection into the neocortex of Fischer rats and the associated epileptic discharges in the Video-EEG were counted and assessed. A comparison was made with test animals that had not received any treatment. The investigations were expanded by the examination of clinical EEGs from patients at the Clinic and Polyclinic for Neurology in Rostock.

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