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Alexander Tonn

[177Lu]Lu-PSMA-617-Therapie beim metastasierten kastrationsresistenten Prostatakarzinom : Dosimetrie der Risikoorgane und Filiae sowie Korrelation von initialer Dosis und SUV-basiertem Therapieansprechen

Universität Rostock, 20.03.2023

https://doi.org/10.18453/rosdok_id00004613

Abstract: This work encompassed 121 therapy cycles. Kidneys, lacrimal glands, and parotid glands as well as the whole body showed specific absorbed doses, dose constants, and effective half-lives. In soft tissue metastases and lymphogenic metastases, a significant correlation was observed between SUV (delta Standard Uptake Value) and tumor dose in the first therapy cycle (p<0.05), but not in bone metastases (p>0.05).

doctoral thesis   free access    


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