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Stephanie Matschos

Erstellung idealer Voraussetzungen für grundlegende sowie translationale in vivo Forschung

Universität Rostock, Januar 2023

https://doi.org/10.18453/rosdok_id00004654

Abstract: Standardized processing of samples and comprehensive characterization of models are crucial for one of the largest private quality-assured biobanks. Comparative pathomorphological analysis and genetic identity testing confirmed the close proximity of the HROC-Xenobank models to the original patient tumors. Additionally, the models accurately recapitulated the mutation profiles of the primary patient tumors, and the clinical situation is represented in the HROC models. This provides an excellent basis for further investigations.

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