| title: |
| Evaluating in vitro toxicity of flavors in alternative nicotine delivery systems utilizing
different in vitro testing strategies |
|
| contributing persons: |
| Selina Rinaldi[VerfasserIn] |
 |
1371837376 |
| Ralf Zimmermann[AkademischeR BetreuerIn] |
|
143922025 |
|
University of Rostock, Institute of Chemistry |
| Tanja Schwerdtle[AkademischeR BetreuerIn] |
 |
0000-0002-4873-7488 |
|
128451335 |
|
Max Rubner-Institut and University of Potsdam, Institute of Nutritional Science, Department
of Food Chemistry |
|
| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
|
38329-6 |
| Universität Rostock. Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
|
| |
| abstract: |
|
The respiratory and local health effects of flavors in alternative nicotine delivery
systems (ANDS) are not well understood. This dissertation aimed to develop an in vitro
risk assessment strategy for ANDS flavors and identify oral nicotine pouch (ONP) ingredients.
Further, the impinger method was optimized for collecting flavored aerosols. Based
on the results, a tiered testing approach is advised using submerged and Air-Liquid
Interface cell models. Further, standardized testing guidelines for flavoring compounds
in emerging ANDS are needed for comprehensive safety assessments.
[English] |
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| document type: |
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| institution: |
| Faculty of Mathematics and Natural Sciences |
|
| language: |
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| subject class (DDC): |
| 500 Natural sciences |
| 540 Chemistry & allied sciences |
| 570 Life science |
|
| |
publication /
production: |
|
Rostock: Universität Rostock
|
|
2025
|
|
| statement of responsibility: |
| vorgelegt von Selina Rinaldi |
|
| notes: |
| Der Volltext der Zeitschriftenartikel ist nur in der Druckausgabe vorhanden |
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| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000003285 |
| created / modified: |
18.07.2025 / 18.07.2025
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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