| title: |
| Establishing the greenhouse-production of FGF21-Transferrin in tobacco seeds and leaves
for oral treatment of non-alcoholic steatosis hepatis NASH |
|
| other title: |
| Etablierung der Gewächshausproduktion von FGF21-Transferrin in Tabaksamen und -blättern
zur oralen Behandlung der nichtalkoholische Steatohepatitis NASH
[translated]
|
|
| contributing persons: |
| Hsuan-Wu Hou[VerfasserIn] |
 |
137268090X |
| Henrik Nausch[AkademischeR BetreuerIn] |
 |
0000-0001-5393-3267 |
|
1030025401 |
|
Fraunhofer-Institut für Molekularbiologie und Angewandte Ökologie IME, Abt. Bioprozessentwicklung |
| Inge Broer[AkademischeR BetreuerIn] |
|
139044809 |
|
Universität Rostock, AUF, Agrobiotechnologie |
| Susanne Klaus[AkademischeR BetreuerIn] |
|
0000-0001-8726-185X |
|
173758878 |
|
Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIfE), Abt. Physiologie
des Energiestoffwechsels |
| Rima Menassa[AkademischeR BetreuerIn] |
|
University of Western Ontario, Biology Department / London Research and Development
Centre, Agriculture and Agri-Food Canada |
|
| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
|
38329-6 |
| Universität Rostock. Agrar- und Umweltwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
10025954-6 |
|
| |
| abstract: |
|
Thesis focuses on the production of a variant of the human fibroblast growth factor
(FGF21) in plants. This factor is supposed to support the liver function, but has
a negative impact on other organs. Hence it has to be directed directly to the liver
and should be unstable to avoid its presence in other organs. An oral intake would
be preferred. Plants provide an excellent platform for the production of orally applied
pharmaceuticals since the cell wall protects the substance from premature degradation
in the gastric system.
[English] |
|
| document type: |
|
| institution: |
| Faculty for Agriculture, Civil and Environmental Engineering |
|
| language: |
|
| subject class (DDC): |
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| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2024
|
|
| statement of responsibility: |
| vorgelegt von Hsuan-Wu Hou |
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000003297 |
| created / modified: |
29.07.2025 / 29.07.2025
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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