| title: |
| Accessible tools for biomolecular data analysis using large-scale knowledge graphs |
|
| contributing persons: |
|
| contributing corporate bodies: |
| Universität Rostock[Grad-verleihende Institution] |
 |
38329-6 |
| Universität Rostock. Fakultät für Informatik und Elektrotechnik[Grad-verleihende Institution] |
|
10085032-7 |
|
| |
| abstract: |
|
The interpretation of biomolecular data is often challenging due to the heterogeneity
in the structural and functional organization of biological systems. In this thesis,
I created knowledge graphs of disease processes, published as interactive Disease
Maps, and developed new tools for their analysis. I present (i) the Atlas of Inflammation
Resolution (AIR), (ii) the two-dimensional enrichment analysis (2DEA) as a novel network-based
enrichment approach, (iii) the Sarcopenia Map linking gastrointestinal diseases and
sarcopenia, and (iv) the MASLD Map investigating steatotic liver diseases.
[English] |
|
| document type: |
|
| institution: |
| Faculty of Computer Science and Electrical Engineering |
|
| language: |
|
| subject class (DDC): |
| 004 Data processing Computer sciences |
| 610 Medical sciences Medicine |
|
| extent: |
|
1 Online-Ressource (xxvi, 195 Seiten)
|
|
| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
Mai 2024
(normalised date: 2024) |
|
| statement of responsibility: |
| vorgelegt von Matti van Welzen |
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
|
|
| RosDok id: |
rosdok_disshab_0000003392 |
| created / modified: |
29.01.2026 / 29.01.2026
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
access
viewer
fulltext