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Franziska Frenck

Langzeit-Video-EEG-Analysen von epileptischen Ratten unter Mycophenolatmofetil-Therapie

Universität Rostock, 02.08.2024

https://doi.org/10.18453/rosdok_id00005269

Abstract: The pilocarpine rat model of temporal lobe epilepsy was used to investigate whether early treatment with mycophenolate mofetil (MMF) after status epilepticus influences seizure frequency. The video-EEG analysis showed no significant reduction in seizure frequency in the MMF group compared to the placebo control. However, seizure activity was less variable in the MMF group, indicating a possible immunological modulation of the course of the disease.

doctoral thesis   free access