goto contents


Robert Bestel

Simulation neuronaler Aktionspotentiale in Hinblick auf Zellform und Physiologie sowie deren Ableitung mittels extrazellulärer Mikroelektroden

Universität Rostock, 2018

https://doi.org/10.18453/rosdok_id00002390

Abstract: In order to investigate the cause for the variety signal shapes present in extracellular measurements of neuronal activity, a detailed neuron model based on the finite element method is created. In a simulation study the impact of geometrical and electrophysiological properties of the neuron as well as several parameters of the neuron-electrode coupling on the derived signal shape is analyzed. Results show a significant dependence of the signal shape on the position of the recording electrode as well as a noticeable influence of the cell-electrode coupling on the signal amplitude.

doctoral thesis   free access    


Portals

OPACGVKDataCite Commons

Rights

all rights reserved

This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz).