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Julia Janke

Synthese und Funktionalisierung von Heterozyklen durch Palladium-katalysierte Kupplungsreaktionen

Universität Rostock, 2019

Abstract: This thesis is dedicated to the synthesis of novel biologically active and fluorescent heterocycles. Based on Friedel-Crafts acylations and palladium(0)-catalyzed CC and CN coupling reactions, a series of new heterocycles were synthesized in high yields. All new products were fully characterized. Additionally, the absorption and emission spectra were measured for selected examples. The thienoquinolones were tested for their inhibition activity against nucleotide pyrophosphatases.

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