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Michela Calanni Pileri

Causes of increased reproductive performance in Dummerstorf high-fertility mouse lines, FL1 and FL2

Universität Rostock, 2023

https://doi.org/10.18453/rosdok_id00004541

Abstract: Dummerstorf high fertility mouse lines are selected for increased fertility. After ~200 generations they doubled their ovulation rate and litter size. This worldwide unique lines can give some insides into the desired highly-informative phenotype of high-fertility, in which those peculiarities of enhanced reproductive performance coexist with characteristics that the literature mostly correlates with a lowering of fertility. The deep analysis of FLs can be a very informative way to get the methods they use to avoid their "bad" characteristics to have an impact in their higher-fertility traits.

doctoral thesis   free access