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	0000-0002-3411-9881
	120065160X

Jan Günther Tönjes

P(III)/P(V) redox cycling catalysis : advances in catalytic Wittig and Appel reactions

Universität Rostock, 14.04.2024

https://doi.org/10.18453/rosdok_id00004760

Abstract: P(III)/P(V) redox cycling catalysis avoids phosphine oxide waste in reactions by reducing it in situ using silanes as terminal reductants. New methods were developed. In a catalytic base-free Wittig (BFW) reaction highly substituted alkenes were formed using environmentally friendly PMHS. An intermediate of the BFW was scavenged with acyl chlorides. Activated alkenes could thus be converted to furans with an unusual substitution pattern. Alcohols and epoxides were converted stereospecifically in a catalytic Appel chlorination under low catalyst loading using small amounts of hexachloroacetone.

doctoral thesis   free access