Exploration of new sustainable synthetic methods for the synthesis of fused pyridines and 4-quinolones based on the domino reaction of chromones and other masked dielectrophiles with nucleophiles

Satenik Mkrtchyan

doi:10.18453/rosdok_id00001477

Satenik Mkrtchyan

Exploration of new sustainable synthetic methods for the synthesis of fused pyridines and 4-quinolones based on the domino reaction of chromones and other masked dielectrophiles with nucleophiles

Universität Rostock, 2015

https://doi.org/10.18453/rosdok_id00001477

Abstract: The present work aimed to study the big potential of chromone derivatives and 1-(2-fluorophenyl)prop-2-yn-1-ones for the synthesis of purine-like fused pyridines and 4-quinolone derivatives. In this regard, a wide range of substituents and substitution patterns are tolerated in the reaction. In addition a new and easy way for synthesis of 4-quinolone derivatives and other fused systems via domino cycloaddition reactions of ortho-fluoro substituted benzoylchromones, 1-(2-fluorophenyl)prop-2-yn-1-ones and aliphatic or aromatic amines were developed.

Dissertation Freier Zugang

Titel:

Exploration of new sustainable synthetic methods for the synthesis of fused pyridines and 4-quinolones based on the domino reaction of chromones and other masked dielectrophiles with nucleophiles

Beteiligte Personen:

Satenik Mkrtchyan[VerfasserIn]
	1064970052
Peter Langer , Prof. Dr.[AkademischeR BetreuerIn]
	132314614
	University of Rostock, Faculty of Chemistry
Bernd Schmidt , Prof. Dr.[AkademischeR BetreuerIn]
	University of Potsdam, Faculty of Chemistry

Beteiligte Körperschaften:

Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution]
	2147083-2

Zusammenfassung:

The present work aimed to study the big potential of chromone derivatives and 1-(2-fluorophenyl)prop-2-yn-1-ones for the synthesis of purine-like fused pyridines and 4-quinolone derivatives. In this regard, a wide range of substituents and substitution patterns are tolerated in the reaction. In addition a new and easy way for synthesis of 4-quinolone derivatives and other fused systems via domino cycloaddition reactions of ortho-fluoro substituted benzoylchromones, 1-(2-fluorophenyl)prop-2-yn-1-ones and aliphatic or aromatic amines were developed. [Deutsch]

Dokumenttyp:

Dissertation

Einrichtung:

Mathematisch-Naturwissenschaftliche Fakultät

Sprache:

Englisch

Sachgruppe der DNB:

540 Chemie

Veröffentlichung /
Entstehung:

Rostock

Rostock: Universität Rostock

2015