| title: |
| Contributions to models of single neuron computation in striatum and cortex |
|
| contributing persons: |
| Youwei Zheng[VerfasserIn] |
 |
1079690727 |
| Adelinde Uhrmacher
, Prof. Dr.[AkademischeR BetreuerIn] |
|
136258794 |
|
Universität Rostock, Institut für Informatik |
| Lars Schwabe
, Dr.[AkademischeR BetreuerIn] |
|
141827793 |
|
Universität Rostock, Institut für Informatik |
| James Surmeier
, Prof. Dr.[AkademischeR BetreuerIn] |
|
Northwestern University, Physiologie |
|
| contributing corporate bodies: |
| Universität Rostock, Fakultät für Informatik und Elektrotechnik[Grad-verleihende Institution] |
|
10085032-7 |
|
| |
| abstract: |
|
A deeper understanding is required of how a single neuron utilizes its nonlinear subcellular
devices to generate complex neuronal dynamics. Two compartmental models of cortex
and striatum are accurately formulated and firmly grounded in the experimental reality
of electrophysiology to address the questions: how striatal projection neurons implement
location-dependent dendritic integration to carry out association-based computation
and how cortical pyramidal neurons strategically exploit the type and location of
synaptic contacts to enrich its computational capacities.
[English] |
|
Neuronale Zellen transformieren kontinuierliche Signale in diskrete Zeitserien von
Aktionspotentialen und kodieren damit Perzeptionen und interne Zustände. Kompartiment-Modelle
werden formuliert von Nervenzellen im Kortex und Striatum, die elektrophysiologisch
fundiert sind, um spezifische Fragen zu adressieren: i) Inwiefern implementieren Projektionen
vom Striatum ortsabhängige dendritische Integration, um Assoziationens-basierte Berechnungen
zu realisieren? ii) Inwiefern nutzen kortikale Zellen den Typ und den Ort, um die
durch sie realisierten Berechnungen zu optimieren?
[German] |
|
| document type: |
|
| institution: |
| Faculty of Computer Science and Electrical Engineering |
|
| language: |
|
| subject class (DDC): |
| 000 Generalities, Science |
| 570 Life science |
|
| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2015
|
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000001455 |
| created / modified: |
03.12.2015 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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