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Meret Herdick

Multimodale MRT-Analysen des cholinergen basalen Vorderhirns über das Alzheimerspektrum

Universität Rostock, 2021

Abstract: The aim of this study was to test the value of three different MRI modalities for the early diagnosis of Alzheimer's disease in the preclinical phase. Functional connectivity (FC), mean diffusivity (MD), and volume in the cholinergic basal forebrain were analyzed, including determination of amyloid changes from CSF. 477 data sets were available for FC analysis and 243 for DTI analysis. Neither the FC nor the MD showed a relevant differentiation of groups in the preclinical stage.

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