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Fatemah Sakr

Untersuchung des Zusammenhangs zwischen Dysregulation im Fettstoffwechsel und pathologischen Markern der Alzheimer-Krankheit

Universität Rostock, 2022

https://doi.org/10.18453/rosdok_id00004328

Abstract: This doctoral dissertation explored novel biomarkers that could reinforce diagnostic accuracy and predict disease progression in the early phases of AD. Such biomarkers are expected to allow the stratification of individuals based on the risk associated with their specific pathology burden, i.e., region-specific cortical amyloidosis and lipids dysregulations. Both approaches enabled higher precision in research participants' characterization, which could be crucial in planning clinical trials and adopting new interventions in prevention trials.

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